oipA “on” status of Helicobacter pylori is associated with gastric cancer in North-Eastern Brazil
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چکیده
منابع مشابه
Analysis of KRAS gene mutation associated with Helicobacter pylori infection in patients with gastric cancer
Objective(s): KRAS proto-oncogene mutation can be considered a diagnostic factor for treating various malignancies. Helicobacter pylori infection, a risk factor for stomach cancer, may cause DNA damage and genetic changes. The aim of the current study was to assess the association of gastric cancer and KRAS mutation, demographic factors, and H. pylori infection.<...
متن کاملRole of autophagy associated with Helicobacter pylori CagA and VacA toxins in gastric cancer
Helicobacter pylori (H. pylori) is a gram-negative microaerophilic bacterium that has been introduced as a cause of mucosal inflammation and gastric cancer. The most important pathogenic factors are VacA and CagA, which are associated with increased disease severity in clinical strains. Autophagy is a protected lysosomal degradation pathway degrading cytoplasmic content and is important in host...
متن کامل(oipA) of Helicobacter pylori
MICROBIOLOGY. For the article ‘‘A Mr 34,000 proinflammatory outer membrane protein (oipA) of Helicobacter pylori’’ by Yoshio Yamaoka, Dong H. Kwon, and David Y. Graham, which appeared in number 13, June, 20, 2000, of Proc. Natl. Acad. Sci. USA (97, 7533–7538), the authors note the following correction. The sequence of the HP0638 gene was incorrect as published. The sequence published was 59-GCT...
متن کاملThe Role of Helicobacter Pylori Virulence Factors in Gastric Cancer
Introduction: Gastrointestinal (GI) cancers are considered among the most important causes of mortality and morbidity. Helicobacter pylori infection has been proven to be highly associated with the development of a variety of gastric diseases such as chronic gastritis, peptic ulcer disease (PUD), mucosa-associated lymphoid tissue (MALT), and gastric cancer (GC). To date, the exact role of the v...
متن کاملBiomarkers of Helicobacter pylori-associated gastric cancer.
Helicobacter pylori-associated gastric cancer is a major cause of morbidity and mortality worldwide, and is predicted to become even more common in developing countries as the population ages. Since gastric cancer develops slowly over years to decades, and typically progresses though a series of well-defined histologic stages, cancer biomarkers have potential to identify asymptomatic individual...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2019
ISSN: 1471-2407
DOI: 10.1186/s12885-018-5249-x